Devoted to meet our commitment
Our journey continues to evolve thanks to our diverse team of experts sharing mutual commitment and dedication, to addressing the immense clinical unmet need for mitochondrial diseases
Our vision
We strive to be the global leader in developing novel Mitochondrial Cell Therapies to treat people stricken with mitochondrial diseases.
Every day, together with the world’s leading scientists, clinicians and patients’ groups we are translating our mitochondrial science into meaningful therapies for mitochondrial diseases – anywhere from ultra-rare to more common ones.
Global Development Plan
Making our therapy available to patients around the world as fast as responsible:
- Strategically-located operations enable a global, multi-site trial approach (IL, US, EU)
- Collaboration with top clinical sites, investigators and Patient Advocacy Groups to develop clinical endpoints and enhance disease understanding
Minovia Mitochondria Research & Development Center
Haifa, Israel
Minovia GMP Processing Plant
Haifa, Israel
Minovia Clinical Site
Sheba Medical Center
Tel Aviv, Israel
Minovia EU Operations
Zug
Switzerland
Clinical Site
United States (coming soon)
Minovia US Operations
Kendall Square, Cambridge
United States
Clinical site Europe
(2021)
Key Accomplishments to-Date
Our ability to execute is driven by our highly experienced executive team, comprehensive regulatory strategy and clinical development plan in partnerships with key physicians and advisors.
Leadership
Natalie Yivgi-Ohana, PhD
Co-founder & CEO
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Natalie Yivgi-Ohana, PhDCo-founder & CEO
Natalie is a life science entrepreneur; led the company since incorporation in 2012. Natalie has twenty years’ experience in mitochondrial research and received her PhD in Biochemistry at The Hebrew University in 2007, after which she performed her postdoctoral fellowship at the Weizmann Institute of Science until 2010. Natalie founded Minovia with a passion to help children and adults with mitochondrial diseases worldwide.
Noa Sher, PhD
Chief Scientist
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Noa Sher, PhDChief Scientist
Noa is highly experienced research leader in the cell therapy space and a molecular and cellular biologist by training. Noa received her PhD in Biochemistry at The Hebrew University in 2007, after which she performed her postdoctoral studies at the Whitehead Institute, MIT, Cambridge, MA and at the Technion Institute of Technology in Israel. She joined Minovia after several years as head of a research team heading preclinical development and characterization of all clinical-stage products at Pluristem, an Israeli-based cell therapy company.
Alan Jacobs, MD, PhD
Chief Medical Officer
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Alan Jacobs, MD, PhDChief Medical Officer
Dr. Alan Jacobs brings over 20 years of experience leading international teams in the research and development of therapeutics and medical devices. His executive experience in companies such as Elan Pharmaceuticals, PerceptiMed and Hemostemix also encompasses clinical development, regulatory affairs, manufacturing, fundraising, grant funding, and Intellectual Property. He has been awarded numerous research grants, fellowships, patents, awards and honors, and has authored many publications. He has served on several committees, including the National Institutes of Health NINDS Stroke Progress Review Group, American Society of Experimental Neurotherapeutics, Health Technology Center Expert Panel Stem Cell Technology, and the American Society of Neurotransplantation and Repair.
Amnon Eylath, ALM
VP Head of Global Quality
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Amnon Eylath, ALMVP Head of Global Quality
Amnon is a seasoned quality executive, experienced in the complete life cycle of drug development, covering biotech, pharmaceutical and cell therapy products, from the R&D stage through nonclinical and toxicological safety studies, clinical trials, process and method development, GMP manufacturing, facility validation, support of regulatory submissions for US/EU/MHRA clinical trials and product approvals, to global distribution of commercial drug products. Amnon has established effective and compliant GXP Quality Systems in the US, Switzerland, EU, and the UK, and managed GXP compliance programs for global clinical trials, for US and International Health Authority inspections (FDA, EMA, MHRA), including for-cause inspections. Amnon is recognized as a thought-leader on the Phase-Appropriate application of GMP to drug development, and on the application of Science and Compliance-based Quality oversight. Amnon has been a volunteer at the ISPE and PDA professional organizations, collaborating with FDA and international regulators on various programs and technical reports.
Nadav Eshkol
Director of Process Development and Manufacturing
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Nadav EshkolDirector of Process Development and Manufacturing
Nadav has more than 10 years of experience in the world of cell therapy, focusing on process development and manufacturing.
He is an expert in developing complex cell therapy processes, optimization, scale-up, tech transfer from development to manufacturing, and process implementation in the manufacturing line, both in start-ups, and in large manufacturing companies.
Before joining Minovia, Nadav led the departments of development and manufacturing at Pluristem, an Israeli-based cell therapy company.
Limor Lior
VP People and Culture
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Limor LiorVP People and Culture
Limor is an experienced senior HR leader with over 18 years of experience in health-tech companies. She has deep professional knowledge of the biotech field, and personal experience as a manager. Before joining Minovia, Ms. Lior worked at Pluristem Therapeutics in various multi-disciplinary roles, including Manufacturing Manager and Organizational Development Senior Manager, and HRBP. She holds an MSc. in Biotechnology Engineer from the Technion, and she’s a certified coach, mediator and group facilitator. Limor is dedicated to the organization’s people, culture, and their continued development, and has a passion for innovative technologies that impact human life.
Board of Directors
John Cox, MBA
Chairman of the Board
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John Cox, MBAChairman of the Board
John joined Minovia Therapeutics in February 2019 and brings over 25 years of experience in biopharmaceuticals. Mr. Cox is currently the Chief Executive Officer of Repertoire Immune Medicines, and was formerly the CEO of Bioverativ, which he built and grew from a new venture with two drugs, Eloctate® and Alprolix® for the treatment of hemophilia A and B. In February 2018 Mr. Cox led Bioverativ to a successful acquisition by Sanofi for $11.6B.
Natalie Yivgi-Ohana PhD
Co-founder, CEO & Board member
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Natalie Yivgi-Ohana PhDCo-founder, CEO & Board member
Natalie is a life science entrepreneur; led the company since incorporation in 2012. Natalie has twenty years’ experience in mitochondrial research and received her PhD in Biochemistry at The Hebrew University in 2007, after which she performed her postdoctoral fellowship at the Weizmann Institute of Science until 2010. Natalie founded Minovia with passion to help children ans adults with mitochondrial diseases worldwide.
Uriel Halavee, PhD
Co-founder & Board Member
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Uriel Halavee, PhDCo-founder & Board Member
Uri is a serial entrepreneur and inventor. He is the former General Manager of Soreq Nuclear Center, Israel. Uri successfully co-founded 6 hi-tech companies: Opal, X-Technologies, Kailight, Radiancy, Sonotron and Oplon.
Ephraim Aharonson, PhD
Co-founder & Board Member
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Ephraim Aharonson, PhDCo-founder & Board Member
Efraim is an Ex-Deputy Head, Israel Institute for Biological Research. He is a former executive at Siemens Israel and a serial angel investor in Israeli start-up companies.
Zeev Milbauer
Board Member
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Zeev MilbauerBoard Member
Zeev is an Angel investor and member of the board of several companies. Zeev is the former Chief Executive Officer and Partner at I.B.I. Investment Banking and brings years of vast experience in brokerage and investment banking.
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